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West Nile Virus Neuroinvasive Disease is indeed the most commonly occurring mosquito-borne disease in the United States. This is primarily due to the widespread presence of the West Nile Virus across various states, particularly affecting both urban and rural areas. The disease's prevalence has been attributed to several factors, including the adaptability of the mosquitoes that transmit the virus and the conditions that facilitate their breeding, such as standing water.

West Nile Virus can lead to severe neurological outcomes, making neuroinvasive disease one of the most serious manifestations of the infection. Reports from the Centers for Disease Control and Prevention (CDC) highlight that West Nile Virus cases are consistently reported each summer and fall, particularly following seasonal peaks in mosquito populations.

In contrast, while malaria, dengue fever, and yellow fever are mosquito-borne diseases, they occur less frequently in the U.S. Malaria has been largely eliminated from the U.S. but can occur through travel, and dengue and yellow fever are not endemic, with cases mainly arising from travel-related exposure. Therefore, West Nile Virus Neuroinvasive Disease stands out as the most common mosquito-borne disease in the country, underscoring the importance of public health efforts to monitor and control mosquito populations.